How can I load a set of variables different per each execution?

Hello,

I was wondering if is possible load a set of variables different per each Test execution, I mean, when the tester going to test, has different values per each test, but when the tester use variables in the test script, these are always the same, even if I create a test Data, then I link with the test script, the test data is always the same, so how can I have different values per each test execution.

Thank you.